Postdoctoral position in computational structural biology
We are looking for a postdoctoral associate with strong background in computational structural biology and protein modeling to work with Dr. Štěpán Timr at J. Heyrovský Institute of Physical Chemistry in Prague.
The successful candidate will become a member of a newly established research team focusing on the computer simulation of cell interior. Using multi-scale molecular models, we aim to elucidate physical and chemical mechanisms governing the spatial organization of metabolic pathways in living cells. The postdoctoral researcher will model protein structures for use in multi-scale simulations of dynamic enzyme assemblies, predict protein–protein, protein–RNA, and protein–metabolite interactions, and evaluate allosteric effects arising from such interactions.
The initial contract period will be for 1 year with a possible extension to up to 5 years and with the possibility of research stays in collaborating laboratories (France, Germany, USA). The research team is integrated into the young and interdisciplinary Department of Computational Chemistry, connecting the physical chemistry and biophysics of proteins and membranes with theoretical enzymology and spectroscopy.
Starting date: January 2023 (can be negotiated).
The ideal candidate has obtained their PhD in computational biology, bioinformatics, computational chemistry, or a related field with the focus on protein structural modeling and/or protein complex prediction. Experience with molecular dynamics simulations, modeling of intrinsically disordered proteins and RNA, as well as with the prediction of liquid–liquid phase separation would be a strong plus. Excellent communication and collaboration skills are essential.
If you are interested, please send us your CV together with a list of publications, your motivation letter, and two contacts as a reference to recruitment jh-inst.cas.cz. Please write in the subject line of your email SC2022_27. For any technical questions, contact stepan.timr jh-inst.cas.cz.
- 25 days paid leave of absence (holidays) per year + 3 days of paid sick-leave in addition to the statutory insurance
- Flexible working-time, the possibility of part-time work, work-life balance
- Lunch vouchers
- Subsidy for sports and cultural activities
- Recreation subsidy, recreation subsidy for children
- Possibility of attending children groups of the CAS
- Possibility to use discounts in recreation centers of the CAS
- Sports goods rental, free parking, trade union library
- Language courses
- Accommodation facilities
- Attractive location
- Health and social insurance paid mandatory by the institute
By providing us with your personal data in your CV, you have allowed J. Heyrovský Institute of Physical Chemistry to process and file your CV in the HR database. Your personal data will be used for the internal HR needs of the J. Heyrovský Institute of Physical Chemistry only. At the same time, you confirm herewith that the personal data as stated in the CV you have sent to us is true and accurate.