Postdoctoral position in computational biophysics and protein modeling

The research team led by Dr. Štěpán Timr at J. Heyrovský Institute of Physical Chemistry in Prague is looking for a postdoctoral associate with a strong background in biomolecular simulation and coarse-grained modeling.

We are a research group focusing on the computer simulation of the cell interior. Using multi-scale molecular models, we aim to elucidate physical and chemical mechanisms governing the organization of metabolic pathways in living cells. Our research team, supported by the prestigious Lumina Quaeruntur Award as well as by a grant from the Czech Science Foundation, is integrated into the interdisciplinary Department of Computational Chemistry, connecting the physical chemistry and biophysics of proteins and membranes with theoretical enzymology and spectroscopy.

The successful candidate will build coarse-grained and ultra-coarse-grained models of glycolytic enzymes and use these models to investigate the formation and the properties of dynamic assemblies formed by the enzymes. The goal will be to enhance our understanding of the spatial organization and regulation of glycolysis. The initial contract period will be for 1 year with a possible extension to up to 2.5 years.

Requirements:The ideal candidate has obtained their PhD in computational biophysics/chemistry, soft-matter physics, or a related field with the focus on protein modeling. Experience with the parameterization of coarse-grained or ultra-coarse-grained biomolecular models would be a strong plus. Excellent communication and collaboration skills are essential.

If you are interested, please send us your CV together with a list of publications, your motivation letter, and two contacts as a reference to (recruitment(at) and (stepan.timr(at) Please write in the subject line of your email SC2023_07. For any questions, contact stepan.timr(at)

Starting date: Summer 2023

Type of contract: Temporary

Job status: Full time

- 25 days paid leave of absence (holidays) per year + 3 days of paid sick-leave in addition  to the statutory insurance
- Flexible working-time, the possibility of part-time work, work-life balance
- Lunch vouchers
- Subsidy for sports and cultural activities
- Recreation subsidy, recreation subsidy for children
- Possibility of attending children groups of the CAS
- Possibility to use discounts in recreation centers of the CAS
- Sports goods rental, free parking, trade union library
- Language courses
- Attractive location
- Health and social insurance paid mandatory by the institute

Selection process

By providing us your personal data in your CV, you have allowed J. Heyrovský Institute of Physical Chemistry to process and file your CV in the HR database. Your personal data will be used for the internal HR needs of the J. Heyrovský Institute of Physical Chemistry only. At the same time you confirm herewith that the personal data as stated in the CV you have sent to us is true and accurate.

Application deadline
2. 5. 2023