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Grants

TOPIC: Biospectroscopy.

Specific ion effects for proteins in solution and related biologically relevant systems

2008-2012

No. 203/08/0114, Grant Agency of the Czech Republic (associated contractor - project leader is affiliated with another institution)

Abstract:
The mechanism of hydration of ions and interaction of ions with biomolecules play an important role in many natural and biotechnological processes. We plan within this proposal to combine computational and experimental tools with the aim to obtain a fundamental molecular understanding of these interactions. We will focus on ion specific interactions with proteins in aqueous and non-aqueous solutions and at lipid membranes. Carefully designed molecular dynamics simulations and experiments will allowus in the end to formulate general rules for interactions of biologically relevant ions with solvated proteins and membranes, as well as rationalize ion effects on the activity of enzymes.

    prof. HOF Martin, Dr. rer. nat. DSc.

    Department: Department of Biophysical Chemistry
    Phone: (+420) 26605 3264, 2011
    Fax: (+420) 286582307
    E-mail: martin.hofatjh-inst.cas.cz
    WWW: http://www.jh-inst.cas.cz/~fluorescence/
    Room: 221,107 c


http://www.rvvi.cz/cep?ss=detail&n=0&h=GA203%2F08%2F0114


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